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Classic glucose transporter type 1 deficiency syndrome

ORPHA:71277· ICD-10 E74.8

Definition

A rare inborn error of metabolism characterized by encephalopathy due to impaired glucose transport into neural cells. The most frequent clinical manifestations are epilepsy, intellectual disability and movement disorder.

Prevalence
1-9 / 1 000 000
Inheritance
Autosomal dominant, Autosomal recessive
Age of onset
Infancy, Neonatal