vitalwiki

Протеасома-асоційований аутозапальний синдром

ORPHA:324977· ICD-10 D89.8· Proteasome-associated autoinflammatory syndrome

Визначення(English summary)

A rare, autosomal recessive autoinflammatory disorder characterized by early-onset erythematous popular/nodular skin eruptions, recurrent fever, possible joint contractures, lipodystrophy, erythematous inflammatory skin changes, joint and muscle involvement (joint contractures, arthralgia, muscle weakness), and hepatosplenomegaly.

Поширеність
<1 / 1 000 000
Успадкування
Autosomal recessive
Вік початку
Childhood, Infancy, Neonatal