vitalwiki

Хвороба Дарє

ORPHA:218· ICD-10 Q82.8· Darier disease

Визначення(English summary)

A rare, genetic keratinization disorder which is classically characterized by keratotic papules, acral pits, and acral wart-like lesions that can be associated with a trigger, and may occur anywhere on the body (including mucosal surfaces). Extracutaneous manifestations may include, nail anomalies, blepharitis, dry eye, neuropsychiatric illness and, recurrent parotid gland obstruction and xerostomia.

Поширеність
1-9 / 100 000
Успадкування
Autosomal dominant
Вік початку
Adolescent, Adult, Childhood