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Glycogen storage disease due to glucose-6-phosphatase deficiency

ORPHA:364· ICD-10 E74.0

Definition

A rare inherited metabolic disease (comprising two major subtypes: type Ia and Ib) characterized by poor tolerance to fasting, growth delay and hepatomegaly resulting from accumulation of glycogen and fat in the liver.

Prevalence
1-9 / 100 000
Inheritance
Autosomal recessive
Age of onset
Infancy, Neonatal