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Амілоїдоз ABri

ORPHA:97345· ICD-10 E85.4+· ABri amyloidosis

Визначення(English summary)

A rare, neurodegenerative disease characterized by progressive cognitive impairment, spastic tetraparesis, and cerebellar ataxia resulting from amyloid deposits in the brain. Spasticity with increased deep tendon reflexes and tone are early symptoms, muscular rigidity evolves later. Progressive mental deterioration usually starts with apathy and impaired memory with progression to complete disorientation.

Успадкування
Autosomal dominant
Вік початку
Adult