Дефіцит альфа-дельта гранул
ORPHA:734· ICD-10 D69.1· Alpha delta granule deficiency
Визначення(English summary)
A rare hemorrhagic disorder due to a constitutional platelet anomaly characterized by moderate to severe deficiency in both platelet alpha-granules and dense bodies, resulting in impaired platelet function and decreased aggregation responses. Patients present increased bleeding tendency with symptoms like easy bruising, or menorrhagia.
- Успадкування
- Autosomal dominant, Autosomal recessive