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Аутосомно-домінантна центронуклеарна міопатія

ORPHA:169189· ICD-10 G71.2· Autosomal dominant centronuclear myopathy

Визначення(English summary)

A rare, autosomal dominant congenital myopathy characterized by numerous centrally placed nuclei on muscle biopsy and clinical features of a congenital myopathy (hypotonia, distal/proximal muscle weakness, rib cage deformities (sometimes associated with respiratory insufficiency), ptosis, ophthalmoparesis and weakness of the muscles of facial expression with dysmorphic facial features.

Поширеність
Unknown
Успадкування
Autosomal dominant
Вік початку
Adolescent, Adult, Childhood, Infancy, Neonatal