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Alobar holoprosencephaly

ORPHA:93925· ICD-10 Q04.2

Definition

A severe form of holoprosencephaly characterized by a single brain ventricle and no interhemispheric fissure. Severe craniofacial features may manifest as cyclopia, ethmocephaly or cebocephaly.

Prevalence
1-9 / 100 000
Inheritance
Multigenic/multifactorial, Not applicable
Age of onset
Infancy, Neonatal