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Hemoglobin H disease

ORPHA:93616· ICD-10 D56.0

Definition

An intermediate form of alpha-thalassemia characterized by increased hemolysis and mild to severe anemia with marked microcytosis and hypochromia. Hemoglobin H disease (HbH) disease belongs to the group of nontransfusion-dependent thalassemia.

Prevalence
1-9 / 1 000 000
Inheritance
Autosomal recessive
Age of onset
All ages