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Congenital thrombotic thrombocytopenic purpura

ORPHA:93583· ICD-10 M31.1

Definition

A hereditary form of thrombotic thrombocytopenic purpura (TTP) characterized by profound peripheral thrombocytopenia, microangiopathic hemolytic anemia (MAHA) and single or multiple organ failure of variable severity.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal recessive
Age of onset
Adult, Childhood, Infancy, Neonatal