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Blastic plasmacytoid dendritic cell neoplasm

ORPHA:86870· ICD-10 C86.4

Definition

A rare and highly aggressive myeloid malignancy characterized by predominant cutaneous involvement with concomitant or subsequent bone marrow, lymph node and visceral involvement, as well as central nervous system (CNS) disease. It derives from the precursors of plasmacytoid dendritic cells (pDC).

Prevalence
1-5 / 10 000
Inheritance
Not applicable
Age of onset
Elderly