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Progressive familial intrahepatic cholestasis type 1

ORPHA:79306· ICD-10 K76.8

Definition

PFIC1, a type of progressive familial intrahepathic cholestasis (PFIC), is an infantile hereditary disorder in bile formation that is hepatocellular in origin and associated with extrahepatic features.

Prevalence
1-9 / 100 000
Inheritance
Autosomal recessive
Age of onset
Infancy, Neonatal