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CPE-related Prader-Willi-like syndrome

ORPHA:633028· ICD-10 Q87.8

Definition

A rare Prader-Willi-like syndrome characterized by intellectual disability, morbid obesity, hypogonadotrophic hypogonadism, hyperphagia and developmental delay. Endocrine disorders including hypothyroidism and insulin resistance can be observed. Unlike Prader-Willi syndrome, profound muscular hypotonia, feeding difficulties in neonates, short stature and growth hormone deficiency are not observed.

Prevalence
<1 / 1 000 000
Age of onset
Childhood, Infancy