vitalwiki

Neonatal ichthyosis-sclerosing cholangitis syndrome

ORPHA:59303· ICD-10 Q80.8

Definition

Neonatal ichthyosis-sclerosing cholangitis (NISCH syndrome) is a very rare complex ichthyosis syndrome characterized by scalp hypotrichosis, scarring alopecia, ichthyosis and sclerosing cholangitis.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal recessive
Age of onset
Neonatal