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Choanal atresia-athelia-hypothyroidism-delayed puberty-short stature syndrome

ORPHA:589856· ICD-10 Q87.8

Definition

A rare genetic multiple congenital anomalies/dysmorphic syndrome characterized by choanal atresia, athelia or hypoplastic nipples, branchial arch abnormalities, external ear malformations, hearing loss, thyroid abnormalities, delayed or absent pubertal development, and short stature. Developmental delay / intellectual disability are variably reported.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal dominant
Age of onset
Neonatal