Familial colorectal cancer Type X
ORPHA:440437· ICD-10 C18.0
Definition
A rare inherited cancer-predisposing syndrome characterized by the fulfilment of the Amsterdam criteria for hereditary nonpolyposis colorectal cancer (HNPCC) but without alterations, either somatic or germline, in the DNA mismatch repair (MMR) genes.
- Inheritance
- Autosomal dominant
- Age of onset
- Adult, Elderly