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Combined immunodeficiency due to OX40 deficiency

ORPHA:431149· ICD-10 D81.8

Definition

Combined immunodeficiency due to OX40 deficiency is a rare combined T and B cell immunodeficiency characterized by susceptibility to develop an aggressive, childhood-onset, disseminated, cutaneous and systemic Kaposi sarcoma.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal recessive
Age of onset
Childhood