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Erythropoietic uroporphyria associated with myeloid malignancy

ORPHA:280379· ICD-10 E80.2

Definition

A rare porphyria characterized by a pre-existing myeloid disorder, skin fragility and blistering on the exposed areas, and hemorrhagic bullae typically on the back of the hands. Urine, plasma and fecal porphyrins are increased.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal recessive
Age of onset
Adult