Bilateral polymicrogyria
ORPHA:268940· ICD-10 Q04.3
Definition
Bilateral polymicrogyria is a rare cerebral malformation due to abnormal neuronal migration defined as a cerebral cortex with many excessively small convolutions. It presents with developmental delay, intellectual disability, seizures and various neurological impairments and may be isolated or comprise a clinical feature of many genetic syndromes. It may also be associated with perinatal cytomegalovirus infection.
- Prevalence
- Unknown
- Inheritance
- Autosomal recessive, X-linked dominant
- Age of onset
- Infancy, Neonatal