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Hypospadias-intellectual disability, Goldblatt type syndrome

ORPHA:2261· ICD-10 Q87.8

Definition

A very rare multiple congenital anomalies syndrome described in three brothers of one South-African family, and characterized by hypospadias and intellectual deficit, in association with microcephaly, craniofacial dysmorphism, joint laxity and beaked nails.

Prevalence
<1 / 1 000 000
Age of onset
Infancy, Neonatal