Corticosteroid-binding globulin deficiency
ORPHA:199247· ICD-10 E27.8
Definition
Corticosteroid-binding globulin deficiency is a rare, genetic, adrenal disease characterized by diminished corticosteroid-binding capacity associated with normal or low plasma corticosteroid-binding globulin concentration and reduced total plasma cortisol levels. Patients typically present chronic pain, fatigue and hypo/hypertension.
- Prevalence
- <1 / 1 000 000
- Inheritance
- Semi-dominant
- Age of onset
- Adult