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Epilepsy-telangiectasia syndrome

ORPHA:1951· ICD-10 G40.8

Definition

A rare, genetic, epilepsy syndrome characterized by epilepsy, palpebral conjunctival telangiectasias, borderline to moderate intellectual disability, diminished serum IgA levels, shortened fifth fingers and dysmorphic facial features (including frontal hirsutism, synophrys, anteverted nostrils, prominent ears, long philtrum, irregular teeth implantation, micrognathia). There have been no further descriptions in the literature since 1978.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal recessive
Age of onset
Childhood