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Cushing syndrome due to bilateral macronodular adrenocortical disease

ORPHA:189427· ICD-10 E24.8

Definition

A rare adrenal Cushing syndrome characterized by bilateral benign adrenal macronodules (>1 cm) that potentially produce autonomously variable levels of cortisol excess. Although in most cases are ACTH-independent, non-suppressed ACTH levels have been described.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal dominant, Not applicable
Age of onset
All ages