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Autosomal recessive centronuclear myopathy

ORPHA:169186· ICD-10 G71.2

Definition

A rare autosomal recessive congenital myopathy characterized by numerous centrally placed nuclei on muscle biopsy and clinical features of a congenital myopathy including facial weakness, ocular abnormalities (ptosis and external ophthalmoplegia) and predominant proximal muscle weakness of variable severity with possible distal involvement.

Prevalence
Unknown
Inheritance
Autosomal recessive
Age of onset
Childhood, Infancy, Neonatal