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Smoldering systemic mastocytosis

ORPHA:158775· ICD-10 D47.0

Definition

A rare, slowly progressive form of systemic mastocytosis (SM) characterized by gradual accumulation of neoplastic mast cells in the visceral organs. Patients typically present with splenomegaly, hypercellular marrow and, in most cases, urticaria pigmentosa-like skin lesions.

Prevalence
Unknown
Inheritance
Autosomal dominant, Unknown
Age of onset
Adult, Elderly