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Distal hereditary motor neuropathy type 1

ORPHA:139518· ICD-10 G12.2

Definition

Distal hereditary motor neuropathy type 1 is a rare neuromuscular disease characterized by slowly-progressive lower limb muscular weakness and atrophy, without sensory impairment. Additional clinical features may include pes cavus, hammertoe and increased muscle tone.

Inheritance
Autosomal dominant
Age of onset
Adolescent, Adult, Childhood