Сприйнятливість до вірусних та мікобактеріальних інфекцій через дефіцит STAT1
ORPHA:391311· ICD-10 D84.8· Susceptibility to viral and mycobacterial infections due to STAT1 deficiency
Визначення(English summary)
A rare, genetic, primary immunodeficiency due to a defect in innate immunity disorder characterized by impaired intracellular signaling from both type I and type II interferons, leading to early-onset, severe, life-threatening intracellular bacterial (typically mycobacteria) and viral (mainly herpes viruses) infections.
- Успадкування
- Autosomal recessive