Синдром зубчастого поліпозу
ORPHA:157798· ICD-10 D12.6· Serrated polyposis syndrome
Визначення(English summary)
A rare, genetic intestinal disease characterized by the presence of multiple (usually large) hyperplastic/serrated colorectal polyps, usually with a pancolonic distribution. Histology reveals hyperplastic polyps, sessile serrated adenomas (most common), traditional serrated adenomas or mixed polyps. It is associated with an increased personal and familial (first-degree relatives) risk of colorectal cancer.
- Поширеність
- 1-9 / 100 000
- Успадкування
- Autosomal dominant, Multigenic/multifactorial, Unknown
- Вік початку
- Adult, Elderly