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Usher syndrome

ORPHA:886· ICD-10 H35.5

Definition

A rare ciliopathy characterized by congenital or childhood onset sensorineural hearing loss (HL) and retinitis pigmentosa (RP) that occurs in a second step with a night blindness and a progressive vision loss and, in some cases, vestibular dysfunction.

Prevalence
1-9 / 100 000
Inheritance
Autosomal recessive
Age of onset
Childhood, Infancy, Neonatal