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EGF-related primary hypomagnesemia with intellectual disability

ORPHA:620368· ICD-10 E83.4

Definition

A rare disorder of magnesium transport characterized by hypomagnesemia due to renal wasting, leading to tetany, early-onset seizures, impaired psychomotor development, and moderate intellectual disability. Secondary hypocalcemia and obesity are absent.

Prevalence
<1 / 1 000 000
Age of onset
Childhood, Infancy