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MERRF

ORPHA:551· ICD-10 G71.3

Definition

A rare mitochondrial oxidative phosphorylation disorder characterized by myoclonic seizures, ataxia, generalized epilepsy, muscle weakness and ragged red fibers in the muscle biopsy.

Prevalence
1-9 / 1 000 000
Inheritance
Mitochondrial inheritance
Age of onset
Adult, Childhood