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VACTERL with hydrocephalus

ORPHA:3412· ICD-10 Q87.8

Definition

A rare multiple congenital anomalies characterized by the association of Vertebral anomalies, Anal atresia, Congenital cardiac disease, Tracheoesophageal fistula, Renal anomalies, and Limb defects (acronym VACTERL) with hydrocephalus. Association with hydrocephalus is relatively rare, may be distinct from VACTERL association in general, and may follow an autosomal recessive pattern of inheritance in some individuals.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal recessive, X-linked recessive
Age of onset
Infancy, Neonatal