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Familial isolated hypoparathyroidism

ORPHA:2238· ICD-10 E20.8

Definition

A rare heterogeneous group of metabolic disorders characterized by abnormal calcium metabolism causing hypocalcemia due to insufficient serum levels of bioactive parathormone (PTH), without other endocrine disorders or developmental defects.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal dominant, Autosomal recessive, X-linked recessive
Age of onset
All ages