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Kaposiform hemangioendothelioma

ORPHA:2122· ICD-10 C49.9

Definition

A rare, locally aggressive, cutaneous or visceral vascular tumor characterized by either superficial lesions presenting as blue-purple infiltrated ill-defined plaques, or deep lesions usually manifesting with coagulation abnormality. They are associated in about 3 out of 4 of cases with potentially lethal thrombocytopenia and consumption coagulopathy (Kasabach-Merritt phenomenon; KMP).

Prevalence
Unknown
Inheritance
Not applicable
Age of onset
All ages