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CODAS syndrome

ORPHA:1458· ICD-10 Q87.8

Definition

A rare multiple congenital anomalies/dysmorphic syndrome characterized by the co-occurrence of Cerebral, Ocular, Dental, Auricular and Skeletal anomalies (acronym CODAS). CODAS syndrome was first reported and named in 1991. As more patients were described, the phenotype was found to be highly variable; patients do not always present with all the aforementioned features.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal recessive
Age of onset
Infancy, Neonatal