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Cerebrocostomandibular syndrome

ORPHA:1393· ICD-10 Q87.8

Definition

Cerebro-costo-mandibular syndrome (CCMS) is characterized at birth by posterior rib gaps and orofacial anomalies reminiscent of Pierre Robin syndrome that include palatal defects (short hard palate, absent soft palate, absent uvula), micrognathia and glossoptosis.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal dominant, Autosomal recessive, Not applicable
Age of onset
Antenatal, Neonatal