Гіпофізарний гігантизм
ORPHA:99725· ICD-10 E22.0· Pituitary gigantism
Визначення(English summary)
A rare endocrine disease characterized by excessively tall stature and rapid growth velocity due to growth hormone excess from a pituitary adenoma/hyperplasia occurring before closure of the epiphyseal growth plates. Additional features may include pubertal delay, visual defects, headache, excessive appetite, hyperhidrosis, menstrual irregularity, prognathism, coarse facial features and large hands/feet.
- Поширеність
- Unknown
- Успадкування
- Autosomal dominant, X-linked dominant
- Вік початку
- Adolescent, Childhood, Infancy