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NLRP3-асоційоване аутозапальне захворювання

ORPHA:208650· NLRP3-associated autoinflammatory disease

Визначення(English summary)

Cryopyrin associated periodic syndrome (CAPS) defines a group of autoinflammatory diseases, characterized by recurrent episodes of systemic inflammatory attacks in the absence of infection or autoimmune disease. CAPS comprises 3 disorders on a continuum of severity: severe CINCA syndrome, intermediate Muckle-Wells syndrome (MWS) and milder familial cold urticaria (FCAS) (see these terms).

Поширеність
1-9 / 1 000 000
Успадкування
Autosomal dominant, Not applicable
Вік початку
Adolescent, Childhood, Infancy, Neonatal