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Cloacal exstrophy

ORPHA:93929· ICD-10 Q64.1

Definition

A rare congenital genitourinary malformation characterized by urogenital, gastrointestinal, skeletal and neurospinal anomalies. It is the most severe part of the spectrum of the exstrophy-epispadias complex (EEC) and is also referred as the OEIS complex (omphalocele, exstrophy, imperforate anus and spinal defects).

Prevalence
1-9 / 1 000 000
Inheritance
Multigenic/multifactorial
Age of onset
Infancy, Neonatal