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Aase-Smith syndrome type 1

ORPHA:916· ICD-10 Q87.8

Definition

A very rare genetic disorder characterised by the following congenital malformations: hydrocephalus (due to Dandy-Walker anomaly), cleft palate, and severe joint contractures.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal dominant
Age of onset
Antenatal, Neonatal