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Wilson disease

ORPHA:905· ICD-10 E83.0

Definition

A rare genetic disorder of copper metabolism presenting with non-specific hepatic, neurologic, psychiatric or ophthalmologic manifestations due to impaired biliary copper excretion and consecutive excessive copper deposition in the body.

Prevalence
1-9 / 100 000
Inheritance
Autosomal recessive
Age of onset
Adolescent, Adult, Childhood, Elderly