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47,XYY syndrome

ORPHA:8· ICD-10 Q98.5

Definition

A rare sex chromosome aneuploidy where males receive an additional Y chromosome, that is characterized clinically by tall stature evident from childhood, macrocephaly, facial features (mild hypertelorism, low set ears, a mildly flat malar region), speech delay and an increased risk for social and emotional difficulties, attention deficit hyperactive disorder and autistic spectrum disorder.

Prevalence
1-5 / 10 000
Inheritance
Not applicable
Age of onset
All ages