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Congenital bile acid synthesis defect type 1

ORPHA:79301· ICD-10 K76.8

Definition

Congenital bile acid synthesis defect type 1 (BAS defect type 1) is the most common anomaly of bile acid synthesis characterized by variable manifestations of progressive cholestatic liver disease, and fat malabsorption.

Prevalence
Unknown
Inheritance
Autosomal recessive
Age of onset
Infancy, Neonatal