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Primary lymphedema

ORPHA:77240

Definition

Primary lymphedema is a lymphatic system malformation characterized by swelling of an extremity that can be associated with other lymphatic effusions, due to an underlying developmental anomaly of the lymphatic system (abnormal lymphangiogenesis). It can be hereditary or not and be congenital or late onset.

Prevalence
1-5 / 10 000
Inheritance
Autosomal dominant, Autosomal recessive
Age of onset
All ages