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Isolated micronodular adrenocortical disease

ORPHA:647782· ICD-10 E24.8

Definition

A rare adrenocortical nodular disease characterized by bilateral, multiple micronodules (<1&nbsp;cm), typically associated with endogenous Cushing syndrome, that occurs predominantly in children and young adults (females in majority). Pigmentation and inter-nodular adrenal cortical atrophy (histological findings present in primary pigmented nodular adrenocortical disease) are generally absent.