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Fructose-1,6-bisphosphatase deficiency

ORPHA:348· ICD-10 E74.1

Definition

Fructose-1,6-biphosphatase (FBP) deficiency is a disorder of fructose metabolism characterized by recurrent episodes of fasting hypoglycemia with lactic acidosis, that may be life-threatening in neonates and infants.

Prevalence
Unknown
Inheritance
Autosomal recessive
Age of onset
All ages