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Very long chain acyl-CoA dehydrogenase deficiency

ORPHA:26793· ICD-10 E71.3

Definition

Very long-chain acyl-CoA dehydrogenase (VLCAD) deficiency (VLCADD) is an inherited disorder of mitochondrial long-chain fatty acid oxidation with a variable presentation including: cardiomyopathy, hypoketotic hypoglycemia, liver disease, exercise intolerance and rhabdomyolysis.

Prevalence
1-9 / 100 000
Inheritance
Autosomal recessive
Age of onset
Infancy, Neonatal