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Short chain acyl-CoA dehydrogenase deficiency

ORPHA:26792· ICD-10 E71.3

Definition

Short-chain acyl-CoA dehydrogenase (SCAD) deficiency is a very rare inborn error of mitochondrial fatty acid oxidation characterized by variable manifestations ranging from asymptomatic individuals (in most cases) to those with failure to thrive, hypotonia, seizures, developmental delay and progressive myopathy.

Prevalence
Unknown
Inheritance
Autosomal recessive
Age of onset
Childhood, Infancy, Neonatal