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Adult-onset autosomal recessive sideroblastic anemia

ORPHA:255132· ICD-10 D64.0

Definition

A very rare non-syndromic autosomal recessive pyridoxine-refractory sideroblastic anemia due to a splice defect of glutaredoxin-5 (GLRX5) described in a single patient with adult onset microcytic hypochromic anemia with liver iron overload and type 2 diabetes.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal recessive
Age of onset
Adult