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Polymalformative genetic syndrome with increased risk of developing cancer

ORPHA:183422

Definition

Polymalformative genetic syndrome with increased risk of developing cancer (PGSIRC) comprises a wide range of syndromes characterized by congenital malformations with a high risk of developing tumors including up to 50 different rare diseases.

Prevalence
1-5 / 10 000
Inheritance
Autosomal dominant, Autosomal recessive
Age of onset
All ages